What description is characteristic of the pathology of interstitial lung disease?

Interstitial lung disease refers to a group of about 100 chronic lung disorders characterized by inflammation and scarring that make it hard for the lungs to get enough oxygen. The scarring is called pulmonary fibrosis. The symptoms and course of these diseases may vary from person to person.

What are the different types of interstitial lung disease?

Some types of interstitial lung disease include:

  • Interstitial pneumonia.
  • Idiopathic pulmonary fibrosis.
  • Nonspecific interstitial pneumonitis.
  • Hypersensitivity pneumonitis.
  • Cryptogenic organizing pneumonia (COP).
  • Acute interstitial pneumonitis.
  • Desquamative interstitial pneumonitis.
  • Sarcoidosis.

What is the pathophysiology of interstitial lung disease?

Interstitial lung disease can be caused by long-term exposure to hazardous materials, such as asbestos. Some types of autoimmune diseases, such as rheumatoid arthritis, also can cause interstitial lung disease. In some cases, however, the causes remain unknown. Once lung scarring occurs, it’s generally irreversible.

What are the pathophysiological effects of interstitial disease?

General pathophysiology of ILD Wound healing and fibrosis are complex, involving numerous cellular processes and molecular pathways (eg, cell adhesion, migration, proliferation, apoptosis, extracellular matrix (ECM) biology, and phenotypic reprogramming).

Is interstitial lung disease restrictive or obstructive?

Some conditions causing restrictive lung disease are: Interstitial lung disease, such as idiopathic pulmonary fibrosis. Sarcoidosis, an autoimmune disease.

What is the difference between COPD and interstitial lung disease?

In IPF, your lungs become scarred, stiff, and thick, and the progressive damage is not reversible. In COPD, the airways, which are branching tubes that carry air within the lungs, become narrow and damaged. This makes people feel out of breath and tired.

What is the pathophysiology of pulmonary fibrosis?

Currently, pulmonary fibrosis is regarded as a disease caused by repeated subclinical injury leading to epithelial damage and subsequent destruction of the alveolar-capillary basement membrane. This process initiates the infiltration of fibrotic cells and the activation of (myo)fibroblasts.

What is the pathological difference between restrictive and obstructive lung disease?

Obstructive lung diseases include conditions that make it hard to exhale all the air in the lungs. People with restrictive lung disease have difficulty fully expanding their lungs with air.

What is the difference between pulmonary fibrosis and idiopathic pulmonary fibrosis?

As pulmonary fibrosis worsens, you become progressively more short of breath. The scarring associated with pulmonary fibrosis can be caused by a multitude of factors. But in most cases, doctors can’t pinpoint what’s causing the problem. When a cause can’t be found, the condition is termed idiopathic pulmonary fibrosis.