Are cancer stem cells tissue-specific?

While normal tissue-specific stem cells provide the basis of tissue homeostasis, a similar hierarchical organization has been identified in tumors which frequently contain a small subpopulation of cells termed cancer stem cells.

What are organ specific stem cells?

These observations include: organ-specific stem cells are senescent; adult stem cells circulate in the organism; stem cell niches are essential for the existence and function of stem cells; adult stem cells can present lineage markers; embryo-like, pluripotent stem cells are present in adult organisms, as shown by the …

What are the 3 types of stem cells and what are their classifications?

What are the Three Types of Stem Cells?

  • Adult Stem Cells (ASCs) Adult, or somatic stem cells, derive from developed organs and tissues that have the ability to renew and generate new cells to replenish dead or damaged tissue in the body.
  • Embryonic Stem Cells (ESCs)
  • Induced Pluripotent Stem Cells (iPSCs)

What is meant by tissue and organ specific stem cells?

ADULT STEM CELLS OR TISSUE-SPECIFIC STEM CELLS In the bone marrow, billions of new blood cells are made every day from blood-forming stem cells. Adult stem cells are tissue-specific, meaning they are found in a given tissue in our bodies and generate the mature cell types within that particular tissue or organ.

Why is gene expression tissue-specific?

Tissue-specific gene expression provides one mechanism by which the same genome can generate differentiated phenotypes among tissues. In our dataset, uniquely expressed genes were largely considered typical for each tissue.

What are the 3 sources of stem cells?

There are several sources of stem cells:

  • Embryonic stem cells. These stem cells come from embryos that are 3 to 5 days old.
  • Adult stem cells.
  • Adult cells altered to have properties of embryonic stem cells.
  • Perinatal stem cells.

What is tissue-specific?

Tissue specificity is defined as the immunological identity of antigens in the lens and other tissues and is shown by the cross-reactivity of one or more lens antigens to one or more antigens present in any extraocular tissue. From: Scientific Foundations of Ophthalmology, 1977.

What are tissue-specific diseases?

An example can be Tuberculosis where the microbes enter through the nose and affect the lungs. Tissue-Specific manifestations are diseases caused in different areas as the point of entry in the body. An example is Malaria where the target is the bloodstream and it slowly spreads throughout the body.