What is the mechanism of action for TRADJENTA?

TRAJENTA® selectively inhibits DPP-4, which leads to a glucose-dependent increase in insulin secretion and a reduction in glucagon secretion thus resulting in an overall improvement in glucose homeostasis. DPP-4 inhibitors prolong the action of GLP-1 and GIP by working in a glucose-dependent way.

What is the action of linagliptin?

Linagliptin is a diabetes drug that works by increasing levels of natural substances called incretins. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also decrease the amount of sugar your liver makes.

What is the drug TRADJENTA used for?

Type 2 Diabetes Medication | Tradjenta® (linagliptin tablets)

What does TRADJENTA do for diabetes?

Tradjenta is an oral diabetes medicine that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating. Tradjenta is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

What class of drug is TRADJENTA?

Tradjenta (linagliptin) is a DPP-4 inhibitor, in the same drug class as Januvia and Onglyza.

What is the side effect of TRADJENTA?

Common side effects may include: runny or stuffy nose, sore throat; cough; or. diarrhea.

What class of drug is Trajenta?

Tradjenta contains the active drug linagliptin. It belongs to a drug class called dipeptidyl peptidase-4 (DPP-4) inhibitors.

What is the difference between metformin and linagliptin?

Linagliptin and metformin are oral diabetes medicines that help control blood sugar levels. Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Linagliptin works by regulating the levels of insulin your body produces after eating.

How does a DPP-4 inhibitor work?

DPP-4 inhibitors work by blocking the action of DPP-4, an enzyme which destroys the hormone incretin. Incretins help the body produce more insulin only when it is needed and reduce the amount of glucose being produced by the liver when it is not needed.

Is trajenta a metformin?

Linagliptin + Metformin HCl (Trajenta Duo) is indicated as add-on to insulin (i.e., triple combination therapy) as an adjunct to diet and exercise to improve glycaemic control in adult patients when insulin and metformin alone do not provide adequate glycaemic control.

What is the difference between Tradjenta and metformin?

Tradjenta (linagliptin) is good add-on medicine for controlling your blood sugar, but may cause body aches. Lowers blood sugar. Glucophage (metformin) is the first choice medicine to control your blood sugar and lower the risk of death from diabetes, although a few people may not tolerate the stomach side effects.

What are Tradjenta side effects?

Mild side effects that have been reported with Tradjenta include:

  • cough.
  • sore throat.
  • stuffy or runny nose.
  • diarrhea*
  • constipation*
  • urinary tract infection (UTI)†
  • weight gain†