What is the caudal regression syndrome?

Caudal regression syndrome is a broad term for a rare complex disorder characterized by abnormal development of the lower (caudal) end of the spine. The spine consists of many small bones (vertebrae) that collectively form the spinal column.

What is lumbar sacral agenesis?

Sacral Agenesis is a congenital condition associated with caudal regression syndrome characterized by the partial or complete absence of sacrum and lower lumbar spine.

When is sacral agenesis diagnosed?

Sacral genesis can be diagnosed by an ultrasound scan usually in the second trimester of the pregnancy, but an earlier scan may also rarely show features suggestive of sacral agenesis. A detailed scan of other baby’s structures is recommended to look for other abnormalities which may be associated with sacral agenesis.

Can you pee with caudal regression syndrome?

If you have caudal regression syndrome, your bladder can be positioned through your abdominal wall. You may have damage to the nerves in your bladder and difficulty controlling urination.

Can you walk with caudal regression syndrome?

If your child’s legs didn’t develop, they may be able to walk using artificial, or prosthetic, legs. If your child has trouble controlling their bladder, they may need a catheter to drain urine.

Can neurogenic bladder cause kidney failure?

If untreated, a neurogenic bladder can cause renal failure and urinary incontinence.

What are the signs and symptoms of neurogenic bladder?

What are the symptoms of neurogenic bladder?

  • Urinary tract infection (UTI)
  • Kidney stones.
  • Urinary incontinence (unable to control urine)
  • Small urine volume during voiding.
  • Urinary frequency and urgency.
  • Dribbling urine.
  • Loss of feeling that the bladder is full.

Can people with sacral agenesis get pregnant?

This condition is associated with an extreme reduction of the xipho-pubic distance and of the pelvic dimensions. It is reasonable to think that this might lead to an increased difficulty in obtaining a spontaneous pregnancy and to a consistently increased risk of maternal and perinatal complications.

What is cause of sacral agenesis?

Sacral agenesis (part of the caudal regression syndrome) is a rare and severe sacral developmental abnormality. It is a congenital malformation of unknown aetiology with possible involvement of genetic and teratogenic factors.

Can you have kids with sacral agenesis?

How common is sacral agenesis?

It is clinically associated with malformation of the hindgut, caudal spinal cord, lower limbs, and the urogenital system. Sacral agenesis has an incidence of 1 in 25,000 live births and is associated with maternal diabetes in approximately 25% cases.