What is an EcoScale?

The EcoScale quantifies the green quality of a synthetic method based upon consideration of six distinct categories: (i) isolated product yield; (ii) cost of chemicals; (iii) safety concerns; (iv) technical set-up; (v) reaction conditions (temperature/time) and (vi) reaction workup/purification methods.

How do you calculate EcoScale?

It is calculated by dividing the yield by 2. For hazard, the maximum score is 20. Each reagent being extremely flammable, toxic, explosive or dangerous for environnement leads to a lost of one point (per hazard). A highly toxic (T+) reagent yields to a lost of 2 points.

What is the EcoScale score?

An ideal reaction has the EcoScale value of 100. The EcoScale score for a particular preparation of the product in a high purity state (> 98%) is calculated by lowering the maximum value of 100 by any applicable penalty points.

Why is E factor important?

Atom economy / E factor are important concepts when designing chemical reactions to ensure sustainability, with atom economy in particular a common measure of how “green” a reaction is. For example, a reaction may have 100% yield, but still generate more waste than product.

How do you calculate effective mass yield?

It is defined as the percentage of the mass of the desired product relative to mass of all non-benign materials used in its synthesis. (%) = 40 37 × 100 = 108% This metric defines yield in terms of the product made from non – toxic materials.

What is a good E factor?

The ideal E factor is 0 and higher E factors are relatively less desirable. E factors that can be tolerated depend upon the value of the product and the amount of product produced.

What is green chemistry explain in detail?

Definition of green chemistry Green chemistry is the design of chemical products and processes that reduce or eliminate the use or generation of hazardous substances. Green chemistry applies across the life cycle of a chemical product, including its design, manufacture, use, and ultimate disposal.

What affects E factor?

E factor=Total mass of waste from processTotal mass of product. The E factor takes into account waste byproducts, leftover reactants, solvent losses, spent catalysts and catalyst supports, and anything else that can be regarded as a waste. Its calculation depends upon what is defined as waste.