What is Valrubicin used for?

Valrubicin solution is used to treat a type of bladder cancer (carcinoma in situ; CIS) that was not effectively treated with another medication (Bacillus Calmette-Guerin; BCG therapy) in patients that can not have surgery right away to remove all or part of the bladder.

What are the side effects of Valrubicin?

Common side effects may include:

  • red or pink urine within the first 24 hours after you receive valrubicin;
  • increased urge to urinate, urine leakage;
  • painful or difficult urination;
  • bladder pain;
  • increased urination at night; or.
  • nausea, stomach pain.

What class is Valrubicin?

Drug type: Valrubicin is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. Valrubicin is classified as an “anthracycline antiobiotic” (for more detail, see “How this drug works,” below).

Is valrubicin chemotherapy?

VALSTAR® (valrubicin) is a chemotherapy medicine that is put into the bladder with a flexible tube called a catheter. If your carcinoma in situ (CIS) bladder cancer did not respond to treatment with Bacillus Calmette-Guerin (BCG), and you can’t be considered for surgery, VALSTAR® may be an option for you.

Is Valrubicin an irritant?

Bladder irritation, with symptoms such as pain, spasm, and frequent urge to urinate, usually occurs. This medication usually will cause your urine to turn a reddish color. This is a normal, harmless effect of the drug and should not be mistaken for blood in your urine.

Who makes Valrubicin?

Endo Pharmaceuticals Inc. VALSTAR ® is a trademark of Endo Pharmaceuticals Inc. or one of its affiliates.

What is intravesical?

(IN-truh-VEH-sih-kul) Within the bladder.

What are the side effects of valsartan?

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  • Bloody urine.
  • decreased frequency or amount of urine.
  • difficult breathing.
  • dizziness, faintness, or lightheadedness when getting up from a lying position.
  • increased thirst.
  • irregular heartbeat.
  • numbness or tingling in the hands, feet, or lips.
  • swelling of the face, fingers, or lower legs.

What is intravesical treatment?

With intravesical therapy, the doctor puts a liquid drug right into your bladder rather than giving it by mouth or injecting it into your blood. The drug is put in through a soft catheter that’s put into your bladder through your urethra. The drug stays in your bladder for up to 2 hours.

What are BCG treatments?

Bacillus Calmette-Guerin (BCG) Treatment. With BCG treatment, your healthcare provider delivers immunotherapy drugs directly to your bladder through a catheter. Unlike oral or injectable drugs, BCG treatment targets cancer cells inside of your bladder without having a negative impact on the rest of your body.

Is valsartan safe in pregnancy?

Do not take valsartan if you are pregnant. If you become pregnant while you are taking valsartan, stop taking valsartan and call your doctor immediately. Valsartan may cause death or serious injury to the fetus when taken in the last 6 months of pregnancy.

Is valsartan a safe drug?

Valsartan is a high blood pressure drug that is considered generally safe and tolerated better by patients than alternative treatments.

Is it safe to take Valrubicin during pregnancy?

If valrubicin is used during pregnancy, or if the patient becomes pregnant while receiving this drug, the patient should be apprised of the potential hazard to the fetus. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Valrubicin is a cancer medication that interferes with the growth and spread of cancer cells in the body. Valrubicin is used to treat bladder cancer that has not spread to other parts of the body.

How is Valrubicin used to treat bladder cancer?

Valrubicin is used to treat bladder cancer that has not spread to other parts of the body. Most people do not have a complete response to valrubicin. You may eventually need surgery to remove your bladder to keep the cancer from becoming metastatic (spreading to other parts of your body).

What is the concentration of Valrubicin in Valstar?

Each vial of VALSTAR contains valrubicin at a concentration of 40 mg/mL in 50% polyoxyl castor oil/50% dehydrated alcohol, USP without preservatives or other additives. The solution is sterile and nonpyrogenic. CLINICAL PHARMACOLOGY Mechanism of Action: