What are some examples of glycoprotein hormones?

Glycoprotein hormones (GPHs) are the most complex molecules with hormonal activity. They include three pituitary hormones, the gonadotropins follicle-stimulating hormone (FSH; follitropin) and luteinizing hormone (LH; lutropin) as well as thyroid-stimulating hormone (TSH; thyrotropin) (1).

Are FSH and LH glycoproteins?

Luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH) from pituitary and chorionic gonadotropin (CG) from placenta are a family of closely related glycoproteins.

Why FSH is a glycoprotein?

Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone. FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland and regulates the development, growth, pubertal maturation, and reproductive processes of the body.

Is GH a glycoprotein hormone?

Glycoprotein hormone α-subunit response to growth hormone (GH)-releasing hormone in patients with active acromegaly: evidence for α-subunit and GH coexistence in the same tumoral cell.

Is GnRH a glycoprotein?

Abstract. The gonadotropin-releasing hormone (GnRH) receptor is a plasma membrane glycoprotein that mediates the binding and intracellular signaling of GnRH. GnRH is responsible for the synthesis and release of the pituitary gonadotropins, luteinizing hormone, and follicle-stimulating hormone.

Is prolactin a glycoprotein?

A positive effect of time, dose, and gonadotropin treatment on prolactin production was seen in each tissue. There was no treatment effect on total protein secretion. Conclusions: All four glycoprotein hormones and their common alpha-subunit stimulate prolactin production.

Is hCG a glycoprotein?

Specific to humans, hCG is a complex glycoprotein composed of two highly glycosylated subunits. The α-subunit is identical to the pituitary gonadotropin hormones (LH, FSH, TSH), contains two N-glycosylation sites, and is encoded by a single gene (CGA).

What type of hormone is ACTH?

Adrenocorticotropic hormone (corticotropin; ACTH) is a 39 amino acid peptide hormone produced by cells of the anterior pituitary gland and carried by the peripheral circulation to its effector organ, the adrenal cortex, where it stimulates the synthesis and secretion of glucocorticoids and, to a more modest extent.