What is the function of the rostral migratory stream?
What is the function of the rostral migratory stream?
The rostral migratory stream (RMS) is a specialized migratory route found in the brain of some animals along which neuronal precursors that originated in the subventricular zone (SVZ) of the brain migrate to reach the main olfactory bulb (OB).
Do humans have a rostral migratory stream?
Throughout the postnatal life of rodents, neural progenitor cells migrate from the subventricular zone (SVZ) of the forebrain through the rostral migratory system (RMS) to the olfactory bulb. Although humans also have an SVZ, until now the existence of an RMS had not been demonstrated.
What is RMS in neurology?
relapsing multiple sclerosis (RMS) relapsing multiple sclerosis. A general term used for all forms of MS that have distinct episodes of relapses, including CIS, RRMS, and active SPMS.
Where is the subventricular zone?
lateral ventricle
The subventricular zone (SVZ) is a region situated on the outside wall of each lateral ventricle of the vertebrate brain. It is present in both the embryonic and adult brain.
What is migratory system?
1 Introduction. The idea of a migratory system is central to geography. Such a system consists of a population distributed over a fixed number of well-defined entities representing, say, the provinces of a nation, cities and their hinterlands, or even the census tracts of a smaller geographical area.
What is a Neuroblast cell?
Neuroblasts are the undifferentiated precursors of the central nervous system (CNS) and, when they segregate from early gastrula (at about 4h of embryogenesis at 25°C), are among the largest cells (diam. 10–12µm) of the embryo.
What is Interkinetic nuclear migration?
Interkinetic nuclear migration (INM) is a common feature of developing neuroepithelia, consisting of the periodic movement of the cell nucleus in phase with cell-cycle progression.
What is the Preplate?
The preplate is the first stage in corticogenesis prior to the development of the cortical plate. The preplate is located between the pia and the ventricular zone. According to current knowledge, the preplate contains the first-born or pioneer neurons. These neurons are mainly thought to be Cajal-Retzius cells.
What is migration stream?
Strictly defined, a migration stream is the total number of moves made during a given migration interval that have a common area of origin and a common area of destination. In practice, it is usually a body of migrants having a common area of origin and a common area of destination.
Do humans have neuroblasts?
In the adult human brain, we find that there are neuroblasts in the anterior ventral SVZ and RMS, but not OB. Interestingly, these neuroblasts appear singly or in pairs without forming chains. Few of these neuroblasts appear to be actively proliferating in vivo.
