Is oxytetracycline soluble in water?
Is oxytetracycline soluble in water?
Oxytetracycline is very slightly soluble in water (313 mg/L), sparingly soluble in ethanol (if similarity with tetracycline holds, the solubility may be in grams/L range). Oxytetracyclin is soluble in acidic or alkaline solutions.
How do you dissolve oxytetracycline?
Oxytetracycline is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, oxytetracycline should first be dissolved in DMSO and then diluted with the aqueous buffer of choice. Oxytetracycline has a solubility of approximately 0.5 mg/ml in a 1:1 solution of DMSO:PBS (pH 7.2) using this method.
What is the difference between tetracycline and oxytetracycline?
Oxytetracycline is a broad-spectrum tetracycline antibiotic, the second of the group to be discovered. Oxytetracycline works by interfering with the ability of bacteria to produce essential proteins. Without these proteins, the bacteria cannot grow, multiply and increase in numbers.
Can injectable oxytetracycline be given orally?
Oxytetracycline can be administered IV or 1M, but the oral route is often preferred for treating populations of food animals.
In which of the following solvent chlortetracycline is soluble?
4-epi-Chlortetracycline (hydrochloride) is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide.
How do you inject oxytetracycline?
Oxytetracycline 50mg Injection may also be used to treat many sexually transmitted diseases. It helps to improve your symptoms and cure the underlying infection. It is given as a drip (intravenous infusion) into a vein under the supervision of a doctor or a nurse.
What is oxytetracycline used for in dogs?
Oxytetracycline is used in both dogs and cats to treat bacterial infections, including respiratory infections of the sinuses, wound infections, pneumonia, infections of the oral cavity and infections of the blood cells.
What is oxytetracycline used for in animals?
Oxytetracycline (OTC) is a broad-spectrum antibiotic, frequently used in veterinary medicine for gastrointestinal and respiratory system diseases, for mainly aerobic microorganisms including Gram-positive/negative bacteria, Rickettsia, Mycoplasma, and Chlamydia species.
How much oxytetracycline can I give my dog?
Dosing Information of Oxytetracycline for Dogs and Cats Medication should never be administered without first consulting your veterinarian. The usual dose is 10 mg per pound (20 mg/kg) every 12 hours orally in both dogs and cats. The usual injection dose is 5 mg per pound (10 mg/kg) every 24 hours intramuscularly.
Is chlortetracycline soluble in water?
Chlortetracycline (trade name Aureomycin, Lederle Laboratories) is a tetracycline antibiotic, the first tetracycline to be identified….Chlortetracycline.
Clinical data | |
---|---|
Melting point | 168 to 169 °C (334 to 336 °F) |
Solubility in water | 0.5–0.6 mg/mL (20 °C) |
Can oxytetracycline be given intravenously?
Oxytetracycline should be administered intravenously slowly over a period of at least 5 minutes. If no improvement occurs within 24 to 48 hours, consult a veterinarian.