What does a high anti cardiolipin IgM mean?
What does a high anti cardiolipin IgM mean?
High levels of the IgM isotype are associated with autoimmune hemolytic anemia, a condition in which an individual’s immune system attacks their red blood cells.
What is anti phospholipid IgM test?
Anti-Phospholipid Screen IgM is an ELISA-based screening test for the quantitative determination of IgM antibodies against cardiolipin, phosphatidyl serine, phosphatidyl inositol, phosphatidic acid, and cofactor beta-2-glycoprotein I in human serum or plasma.
What causes high Anticardiolipin IgM?
Cardiolipin is a phospholipid, or a kind of fat in the blood. The levels of these antibodies are often high in people with abnormal blood clotting, autoimmune diseases like lupus, or repeated miscarriages.
What is anti cardiolipin IGG?
– Anticardiolipins are antibodies produced by the immune system against the platelet membrane phospholipids responsible for the coagulation of blood clots.
What is considered a high cardiolipin level?
Reference Interval
| <=14 GPL | Negative |
|---|---|
| 15-19 GPL | Indeterminate |
| 20-80 GPL | Low to Moderately Positive |
| 81 GPL or above | High Positive |
What does a positive antiphospholipid antibody mean?
High levels of this antibody may mean you have a higher risk for blood clots. Your healthcare provider can’t predict when a clot may happen. You may need a second test in about 12 weeks to confirm the results. A positive result doesn’t mean you need treatment.
What does cardiolipin antibody positive mean?
Causes of positive levels of Cardiolipin Antibodies Cardiolipin antibodies are temporarily detected in the blood due to infections such as HIV/AIDS, certain drugs, and in elderly people. These antibodies are often detected with other antiphospholipid antibodies in certain autoimmune conditions such as lupus.
What does Anticardiolipin IgM test for?
Description. The Anticardiolipin Antibodies Test, or ACA Blood Test, aids in the diagnosis of antiphospholipid syndrome (APS). APS is an autoimmune disorder that produces anticardiolipin antibodies. These antibodies interfere with the blood clotting process, which can result in inappropriate or excessive clotting.
What is the normal range for cardiolipin IgM?
Ref range previously listed as: IgG: 0-14 (Negative), 15-19 (Indeterminate), 20-80 (Low to Medium Positive), 81 or higher (High Positive), IgM: 0-12 (Negative), 13-19 (Indeterminate), 20-80 (Low to Medium Positive), 81 or higher (High Positive) 3/3/2017: Updated reference range with new testing kit.
What foods to avoid if you have APS?
Safe dietary choices. You might need to avoid eating large amounts of vitamin K-rich foods such as avocado, broccoli, Brussels sprouts, cabbage, leafy greens and garbanzo beans. Alcohol can increase warfarin’s blood-thinning effect. Ask your doctor if you need to limit or avoid alcohol.
