What does EBV VCA IgG positive mean?

The presence of VCA IgG antibodies indicates that an EBV infection has occurred at some time recently or in the past. The presence of VCA IgM antibodies and the absence of antibodies to EBNA mean that the infection has occurred recently. The presence of antibodies to EBNA means that the infection occurred in the past.

How do you read EBV VCA IgG?

If someone has positive VCA-IgG and EA-D IgG tests, then it is highly likely that the person has a current or recent EBV infection. If the VCA-IgM is negative but VCA-IgG and an EBNA antibody are positive, then it is likely that the person tested had a previous EBV infection.

How do I read my EBV antibody panel?

Interpretation. The test has 3 components: viral capsid antigen (VCA) IgG, VCA IgM, and Epstein-Barr nuclear antigen (EBNA). Presence of VCA IgM antibodies indicates recent primary infection with Epstein-Barr virus (EBV). The presence of VCA IgG antibodies indicates infection sometime in the past.

What does a positive EBV VCA IgM mean?

The presence of VCA IgM and VCA IgG without EBNA-1 IgG indicates acute infection, whereas the presence of VCA IgG and EBNA-1 IgG without VCA IgM is typical of past infection.

When does EBV IgG turn positive?

Anti-VCA IgG appears in the acute phase of EBV infection, peaks at two to four weeks after onset, declines slightly then persists for the rest of a person’s life.

What is a normal EBV VCA IgG level?

Optimal Result: 0 – 17.9 U/mL. EBV-VCA, IgG is an antibody (protein) that is produced by the body in an immune response to an Epstein-Barr virus antigen. EBV stands for Epstein-Barr virus.

What do my EBV results mean?

People are considered to have a primary EBV infection if they have anti-VCA IgM but do not have antibody to EBNA. Other results that strongly suggest a primary infection are a high or rising level of anti-VCA IgG and no antibody to EBNA after at least four weeks of illness.

How long does EBV IgG stay positive?

Anti-EA IgG appears in the acute phase of illness and generally falls to undetectable levels after three to six months. In many people, detection of antibody to EA is a sign of active infection.

What are normal EBV IgG levels?

According to the manufacturer’s recommendations, EBNA-1 IgG levels <5 U/ml were considered negative, levels between 5–20 U/ml were considered equivocal, and levels ≥20 U/ml were considered positive.