What is the meaning of ACT in drugs?

Abstract. Artemisinin-based combination therapies (ACTs) are the best anti-malarial drugs available now. Artemisinin enhances efficacy and has the potential of lowering the rate at which resistance emerges and spreads.

Which is the best treatment for malaria?

The preferred antimalarial for interim oral treatment is artemether-lumefantrine (Coartem™) because of its fast onset of action. Other oral options include atovaquone-proguanil (Malarone™), quinine, and mefloquine.

What are the drugs in artemisinin combination therapy?

Fast acting artemisinin-based compounds are combined with a drug from a different class. Companion drugs include lumefantrine, mefloquine, amodiaquine, sulfadoxine/pyrimethamine, piperaquine and chlorproguanil/dapsone. Artemisinin derivatives include dihydroartemisinin, artesunate and artemether.

What is the meaning of ACT for malaria?

Artemisinin-based combination treatments (ACTs) are now generally accepted as the best treatments for uncomplicated falciparum malaria. They are rapidly and reliably effective.

Is artemether an ACT?

Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp.

Is artesunate an ACT?

Four ACTs are currently recommended by WHO: artesunate–mefloquine, artesunate–sulfadoxine–pyrimethamine (SP), artesunate–amodiaquine, and artemether–lumefantrine.

Is artemether lumefantrine an ACT?

Artemether–lumefantrine (AL) is one of the most commonly used ACT in sub-Saharan Africa and is often co-administered with ART in malaria-HIV co-infected individuals.

What is the best drug for malaria and typhoid?

Commonly prescribed antibiotics

  • Ciprofloxacin (Cipro). In the United States, doctors often prescribe this for adults who aren’t pregnant.
  • Azithromycin (Zithromax). This may be used if a person is unable to take ciprofloxacin or the bacteria are resistant to ciprofloxacin.
  • Ceftriaxone.