What are Descemet folds?

Descemet folds are associated with corneal edema due to endothelial dysfunction from infections, from infiltrations, or following surgery. Descemet folds also are associated with corneal inflammation due to infections or infiltrations or following surgery.

What causes folds in Descemet’s membrane?

The main cause of tears or folds in Descemet’s membrane is congenital glaucoma. Congenital glaucoma can cause breaks in Descemet’s membrane due to raised intraocular pressure with stretching of the cornea. The breaks typically have a horizontal orientation and are called Haab’s striae.

What is Descemet membrane of cornea?

Descemet’s membrane- which is the basement membrane for the corneal endothelium- is a dense, thick, relatively transparent and cell-free matrix that separates the posterior corneal stroma from the underlying endothelium.

Where is the Descemet membrane located?

Descemet’s membrane (or the Descemet membrane) is the basement membrane that lies between the corneal proper substance, also called stroma, and the endothelial layer of the cornea.

How do you treat a corneal fold?

Medication Summary. Medical treatment of Descemet folds requires the treatment of the underlying cause of ocular inflammation. This includes topical steroidal, nonsteroidal, and osmotic agents, as well as topical antibiotics, as needed, for ocular infection.

Can cataract surgery cause corneal damage?

Damage to the cells on the back layer of the cornea (endothelial cells) related to the cataract surgery. Even “perfect” cataract surgery can occasionally cause corneal swelling that doesn’t resolve on its own.

For what purpose is Descemet used?

The procedure is used to treat corneal edema in the setting of endothelial dystrophies (such as Fuchs corneal dystrophy and posterior polymorphous corneal dystrophy), pseudophakic bullous keratopathy, iridocorneal endothelial (ICE) syndrome, endothelial failure in the setting of prior intraocular surgery or of a …

What is a corneal fold?

Definition. Presence of folds in the Descemet membrane, which is the basement membrane of the endothelial (inner) cell layer of the cornea. Descemet membrane folds are generally a manifestation of inflammation or edema of the cornea. [ from HPO]

What causes folds during cataract operation?

The presence of posterior capsule folds occurs after lens implantation. The folds are oriented along the longitudinal axis of the intraocular lens (IOL) as a result of the disparity in size of the IOL and capsular bag [5].