What type of drug is Eliglustat?

Eliglustat is in a class of medications called enzyme inhibitors. It works by preventing the body from producing the fatty substance so that less of it will build up in the body and cause symptoms.

How does eliglustat work?

Eliglustat works by inhibiting UDP-glucosylceramide synthase, the first enzyme that catalyzes the biosynthesis of glycosphingolipids, thus reducing the load of glucosylceramide influx into the lysosome.

What is Cerdelga used for?

CERDELGA is a prescription medicine used for the long-term treatment of Gaucher disease type 1 (GD1) in adults who are CYP2D6 extensive metabolizers (EMs), intermediate metabolizers (IMs), or poor metabolizers (PMs) as detected by an FDA-cleared test.

What is Gaucher disease?

Gaucher (go-SHAY) disease is the result of a buildup of certain fatty substances in certain organs, particularly your spleen and liver. This causes these organs to enlarge and can affect their function. The fatty substances also can build up in bone tissue, weakening the bone and increasing the risk of fractures.

Is furazolidone an antibiotic?

Furazolidone is a member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera.

Who manufactures Cerdelga?

Paris, August 19, 2014 – Genzyme, a Sanofi company (EURONEXT: SAN and NYSE: SNY), announced today that the U.S. Food and Drug Administration (FDA) has approved Cerdelga(TM) (eliglustat) capsules, the only first-line oral therapy for certain adult Gaucher disease type 1 patients.

Is Cerdelga an ERT?

Cerdelga is different from enzyme replacement therapy (ERT) infusions. Cerdelga is a noninvasive, oral medication called a substrate reduction therapy (SRT).

What disease does Adam Rose have?

Gaucher’s disease or Gaucher disease (/ɡoʊˈʃeɪ/) (GD) is a genetic disorder in which glucocerebroside (a sphingolipid, also known as glucosylceramide) accumulates in cells and certain organs.

Is furazolidone safe?

The inclusion of furazolidone in a treatment regimen for H pylori infection is, at least, controversial, and it does not appear to be safe.

What are the side effects of furazolidone?

Common side effects of Furoxone (furazolidone) include:

  • lowered blood pressure,
  • hives,
  • fever,
  • joint pain,
  • rash,
  • stomach upset,
  • nausea,
  • vomiting,