What is a Type 2 beta turn?

Type I and Type II Reverse Turns Such a structure is known as the Reverse turn or the beta turn (because it is found joining adjacent antiparallel sequences of beta sheet).

How often is Mircera given?

Mircera can be administered once every two weeks or once monthly to patients whose hemoglobin has been stabilized by treatment with an ESA (see Table 1). The dose of Mircera, given as a single intravenous or subcutaneous injection, should be based on the total weekly ESA dose at the time of conversion.

What amino acids are in beta turns?

Gratifyingly, the turn propensities of amino acids at different positions of various protein β-turn types obtained through statistical analysis by directed evolution and phage-display correlate well with work on model peptides in showing glycine, proline, asparagine, and aspartic acid to be the most common β-turn- …

How many amino acids are in a beta turn?

four amino acids
A β-turn is composed of four amino acidsa. The Ω loop, as a secondary-structural motif in globular proteins, was first described in 1986. These are a six-amino-acid or longer backbone motif.

Which amino acids are commonly found in β turns?

How do Type I and Type II differ?

People with type 1 diabetes don’t produce insulin. You can think of it as not having a key. People with type 2 diabetes don’t respond to insulin as well as they should and later in the disease often don’t make enough insulin. You can think of it as having a broken key.

What is a gamma turn?

Gamma-turns are the second most commonly found turns (after beta-turns) in proteins. By definition, a gamma-turn contains three consecutive residues (denoted by i, i + 1, i + 2) and a hydrogen bond between the backbone COi and the backbone NHi+2 (see Fig. 1). There are two types of gamma-turns: classic and inverse7.

How is Mircera dosed?

MIRCERA® is administered either intravenously or subcutaneously in adult patients and only intravenously in pediatric patients. When administered subcutaneously, MIRCERA® should be injected into the abdomen, arm, or thigh. MIRCERA® is packaged as single-dose prefilled syringes.

How long does it take for Mircera to work?

It may take 2 to 6 weeks before your red blood cell count increases. Tell your doctor if your symptoms do not get better or if they get worse.