Can bone marrow transplant cause death?
Can bone marrow transplant cause death?
Besides the risk of relapse, hematopoietic stem cell transplantation (HSCT) remains associated with significant early and late treatment related mortality (TRM). Infections, toxicity, and (after allogeneic HSCT only), graft-vs. -host disease (GVHD) are the main causes of death.
Is a bone marrow transplant high risk?
Stem cell or bone marrow transplants are complex treatments that carry a significant risk of serious complications. It’s important that you’re aware of both the risks and possible benefits before treatment begins. You may wish to discuss them with your treatment team and your family.
Does a bone marrow transplant shorten your life?
Overall, the life expectancy of patients who underwent BMT was 20.8% lower than expected, translating into 8.7 years of life lost, reported Smita Bhatia, MD, MPH, of the Institute for Cancer Outcomes and Survivorship at the University of Alabama in Birmingham, and colleagues.
Can stem cell transplants cause death?
Despite improvements in therapy, approximately 5% of patients who undergo autologous stem cell transplantation (ASCT) experience early mortality (EM), death within 1 year of transplant (EM post-ASCT). Such patients tend to have few comorbidities suggesting their EM is owing to aggressive underlying disease.
Is it harmful to donate bone marrow?
Bone marrow donation Bone marrow stem cells are collected from a section of the pelvic bone under general anesthesia. The most serious risk associated with donating bone marrow involves the use and effects of anesthesia during surgery. The surgery might cause tiredness, weakness, and mild back or hip pain.
What is the most common complication of bone marrow transplantation?
Bacterial infections are the most common. Viral, fungal and other infections can also occur. Some infections can develop later on, weeks to months after the transplant. Infections can cause extended hospital stay, prevent or delay engraftment, cause organ damage, and may be life threatening.
