What is midazolam hydrochloride used for?

Midazolam injection is used before medical procedures and surgery to cause drowsiness, relieve anxiety, and prevent any memory of the event. It is also sometimes given as part of the anesthesia during surgery to produce a loss of consciousness.

What is the therapeutic class of midazolam?

Midazolam is in a class of medications called benzodiazepines. It works by slowing activity in the brain to allow relaxation and sleep.

How does midazolam work pharmacology?

Midazolam acts on glycine receptors and produces a muscle-relaxing effect. Almost all the pharmacologic effects, including sedation, anxiolysis, anterograde amnesia, and anticonvulsant effect, can are explainable through its action on GABA receptors.

What is the indication of midazolam?

Indicated for promoting preoperative sedation, anxiolysis, anesthesia induction, or amnesia. Indicated for the treatment of status epilepticus in adults.

What are the effects of midazolam?

It helps to cause drowsiness, decrease anxiety, and to decrease your memory of the surgery or procedure. This medication may also be used to help with anesthesia or to sedate people who need a tube or machine to help with breathing. Midazolam works by calming the brain and nerves.

What are the contraindications of midazolam?

The following conditions are contraindicated with this drug….Conditions:

  • drug abuse.
  • closed angle glaucoma.
  • chronic heart failure.
  • constriction of blood vessels of the extremities.
  • obstructive pulmonary disease.
  • decreased lung function.
  • hardening of the liver.
  • acute kidney failure.

What is the pharmacokinetics of midazolam?

Six single-dose pharmacokinetic studies involving healthy adults yield pharmacokinetic parameters for midazolam in the following ranges: volume of distribution (Vd), 1 to 3.1 L/kg; elimination half-life, 1.8 to 6.4 hours (mean approximately 3 hours); total clearance (Cl), 0.25 to 0.54 L/hr/kg.

What is the side effect of midazolam?

drowsiness, hiccups, “oversedation,” or. injection site reactions (pain, swelling, redness, stiffness, blood clots, and tenderness).

What are contraindications of midazolam?

What is the antidote for midazolam?

Conclusion: Flumazenil in a dose of 0.15 mg is a safe drug that reverses the sedative effect of midazolam.

What is another name for midazolam?

Midazolam, sold under the brand name Versed, among others, is a benzodiazepine medication used for anesthesia, procedural sedation, trouble sleeping, and severe agitation.

What is Midazolam used for?

Midazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that is used to help you relax before having a minor surgery, dental work, or other medical procedure. Midazolam may also be used for purposes not listed in this medication guide. Warnings

What is the drug midazolam?

Versed (midazolam) is a benzodiazepine, a type of drug that causes relaxation, sleepiness, and partial or complete loss of memory during use. It’s commonly used to help you better tolerate a medical procedure.

What does midazolam do?

agitation

  • restlessness
  • uncontrollable shaking of a part of the body
  • stiffening and jerking of the arms and legs
  • aggression
  • seizures
  • uncontrollable rapid eye movements
  • hives
  • rash
  • itching

    • How is versed metabolized?

    cough,wheezing,trouble breathing;

  • slow heart rate;
  • a light-headed feeling,like you might pass out;
  • tremors; or
  • confusion,agitation,hallucinations,unusual thoughts or behavior.